Preheat oven to 350ºF. In a small bowl, combine spices for the spice mixture. In another small bowl, combine ingredients for the Lemon Zest Crème Fraîche. (The Crème Fraîche can be skipped all together, or substituted with goat cheese!)
Toss the butternut squash with oil and 1 tablespoon of the spice mixture. Bake for 20-30 minutes depending on the size of the cubes. Toss halfway through cook time. Remove from oven and toss butternut squash in adobo sauce (use 2 tablespoons for more heat). Drizzle with some of the Lemon Zest Crème Fraîche.