Preheat oven to 500ºF. Combine the bread and milk in a large bowl and soak for 10 minutes. Add the turkey, eggs, cheese, pancetta, onion, garlic, 1 tablespoon of the ketchup, the parsley, oregano, dried breadcrumbs, and salt and pepper to taste. Mix well with your hands.
Shape into an 8”x5” loaf and transfer to a rimmed baking sheet. Bake for 15 minutes. Reduce the heat to 325ºF and slather the remaining 1/4 cup ketchup all over the top of the loaf. Bake until a meat thermometer inserted in the center of the loaf reads 165ºF, about 45 minutes. Let the meat loaf rest for 10 minutes, then transfer to a platter and serve.