Preheat oven to 375°F. Bake 8 slices bacon on wire rack set over a rimmed baking sheet or on slotted broiler pan to crisp.
Finely chop remaining 4 slices bacon. Heat skillet with 1 tablespoon oil, 1 turn of the pan. Add bacon and render 2 minutes. Add onions, season with salt and pepper, and cook over moderate heat until very tender, 12-15 minutes. Add Worcestershire, light brown sugar and beer, and simmer a minute more.
Make the base sauce for the mac: Bring cream, garlic clove and mustard to a low boil and simmer 5 minutes to thicken. Remove garlic clove and add in cheese; stir to melt.
Combine bacon and onions with sauce and pasta, and place everything in a casserole dish.
Place pretzel crumbs in bowl. In a small pot, melt butter over medium heat with garlic, swirl a minute or so, then add hot sauce and swirl to mix. Pour over pretzels, toss with cheese and parsley, and sprinkle over the casserole.
Bake to bubbly and brown, and serve.